mammaglobin-B; lacryglobin; lipophilin-C; mammaglobin-2; secretoglobin family 2A member 1 (SCGB2A1, LIPHC, MGB2, UGB3)
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Function
- may bind androgens & other steroids
- may also bind estramustine, a chemotherapeutic agent used for prostate cancer
- may be under transcriptional regulation of steroid hormones
- heterodimer of a lipophilin A & a lipophilin C (mammaglobin B)
Structure
- belongs to the secretoglobin family, lipophilin subfamily
Expression
- expressed in steroid responsive tissues (prostate, testis, uterus, breast & ovary)
- expressed in thymus, trachea, kidney, & salivary gland