anamorsin; cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog (CIAPIN1)

Function

• may be required for the maturation of extramitochondrial Fe/S proteins (putative)
• has anti-apoptotic effects in the cell
• role in negative control of cell death upon cytokine withdrawal
• promotes development of hematopoietic cells

Structure

belongs to the anamorsin family

Compartment

cytoplasm. nucleus

Alternative splicing

named isoforms=3

Expression

• ubiquitously expressed
• highly expressed in heart, liver & pancreas

Notes

• 'ana-mors-in' means 'anti-death molecule' in latin

More general terms

• anti apoptotic protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57019
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57019
• OMIM: https://mirror.omim.org/entry/608943
• UniProt: http://www.uniprot.org/uniprot/Q6FI81.html