spectrin beta chain, brain 4; spectrin, non-erythroid beta chain 4; beta-V spectrin; BSPECV (SPTBN5 SPTBN4)

Function

• probably associates with an alpha chain

Structure

• belongs to the spectrin family
• contains 2 CH (calponin-homology) domains
• contains 1 PH domain
• contains 31 spectrin repeats

Compartment

• cytoplasm, cytoskeleton
• detected prominently in the outer segments of photoreceptor rods & cones & in the basolateral membrane & cytosol of gastric epithelial cells

Expression

• expressed at very low levels in many tissues
• strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, & heart

More general terms

• beta-spectrin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51332
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51332
• OMIM: https://mirror.omim.org/entry/605916
• UniProt: http://www.uniprot.org/uniprot/Q9NRC6.html