phosphatase-2A 48 kD regulatory subunit B (PP2A, subunit B, PR48 isoform; PPP2R3B)

Function

• B regulatory subunit might modulate substrate selectivity & catalytic activity, & also might direct the localization of the catalytic enzyme to a particular subcellular compartment
• interacts with N-terminal region of CDC6

Structure

contains 1 EF-hand domain

Compartment

• nucleus

Genetics

• gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X & Y chromosomes

More general terms

• phosphatase-2A B subunit

Additional terms

• phosphatase-2A (ceramide-activated protein phosphatase)

Database

• OMIM: https://mirror.omim.org/entry/300339
• UniProt: http://www.uniprot.org/uniprot/Q9Y5P8.html