histone demethylase UTY; ubiquitously transcribed TPR protein on the Y chromosome; ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (UTY)

Function

• histone demethylase (putative)
• interacts with TLE1 & TLE2 (putative)

Cofactor:

• ascorbate (putative)
• Fe+2 (putative)

Structure

• belongs to the UTX family
• contains 1 JmjC domain
• contains 8 TPR repeats

Compartment

nucleus (putative)

Alternative splicing

• named isoforms=3
• additional isoforms seem to exist

More general terms

• Y chromosome protein
• tetratricopeptide repeat protein
• histone demethylase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7404
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7404
• OMIM: https://mirror.omim.org/entry/400009
• UniProt: http://www.uniprot.org/uniprot/O14607.html