regulator of G-protein signaling 14 (RGS14)

Function

• inhibits signal transduction by increasing GTPase activity of G-alpha subunits increasing the amount of inactive GDP-bound form

Structure

• contains 1 Goloco domain
• contains 2 RBD (Ras-binding) domains
• contains 1 RGS domain

Compartment

membrane (putative)

Alternative splicing

named isoforms=4

More general terms

• regulator of G-protein signaling
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10636
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10636
• OMIM: https://mirror.omim.org/entry/602513
• UniProt: http://www.uniprot.org/uniprot/O43566.html