vacuolar protein sorting-associated protein 16 (hVPS16, VPS16)

Function

• vesicle-mediated protein trafficking to lysosomal compartments & in membrane docking/fusion reactions of late endosomes/ lysosomes.
• component of large hetero-oligomeric complex together with VPS11, VPS18 & VPS33A
• interacts with STX7

Compartment

• endosome, late endosomal membrane
• lysosome, lysosomal membrane
• peripheral membrane, cytoplasm

Alternative splicing

named isoforms=2

Expression

ubiquitous

More general terms

• vacuolar protein sorting-associated protein (VPS)

Database

• OMIM: https://mirror.omim.org/entry/608550
• UniProt: http://www.uniprot.org/uniprot/Q9H269.html