vacuolar protein sorting-associated protein 11 (hVPS11, RING finger protein 108, VPS11, RNF108, PP3476)

Function

• vesicle-mediated protein trafficking to lysosomal compartments & in membrane docking/fusion reactions of late endosomes/lysosomes
• component of large hetero-oligomeric complex together with VPS16, VPS18 & VPS33A
• interacts with STX7

Compartment

• endosome, late endosomal membrane
• lysosome, lysosomal membrane
• peripheral membrane

Expression

• ubiquitous
• expression in heart > lung

More general terms

• vacuolar protein sorting-associated protein (VPS)
• ring finger protein

Database

• OMIM: https://mirror.omim.org/entry/608549
• UniProt: http://www.uniprot.org/uniprot/Q9H270.html