nucleoside diphosphate kinase-5 homolog (NDK-H 5, NDP kinase homolog 5, nm23-H5, testis-specific nm23 homolog) (Inhibitor of p53-induced apoptosis-beta, IPIA-beta, protein expressed in nonmetastatic cells 5, NME5)

Function

• does not seem to have NDK kinase activity
• confers protection from cell death by Bax & alters cellular levels of several antioxidant enzymes including Gpx5
• role in spermiogenesis by increasing ability of late-stage spermatids to eliminate reactive oxygen species (putative)

Structure

belongs to the NDK family

Expression

• specifically expressed in testis germinal cells

More general terms

• nucleoside diphosphate kinase (NDK) or NDP kinase
• testis-specific protein

Database

• OMIM: https://mirror.omim.org/entry/603575
• UniProt: http://www.uniprot.org/uniprot/P56597.html