autophagy protein 12-like; ubiquitin-like protein ATG12; autophagy-related protein 12; APG12-like (ATG12, APG12, APG12L)

Function

• ubiquitin-like protein required for autophagy
• conjugated to ATG3 & ATG5

Structure

• shares weak sequence similarity with ubiquitin family, but contains an ubiquitin superfold
• the C-terminal Gly is required for isopeptide linkage
• belongs to the ATG12 family

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

Expression

ubiquitous

More general terms

• autophagy protein (autophagy-related protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9140
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9140
• OMIM: https://mirror.omim.org/entry/609608
• UniProt: http://www.uniprot.org/uniprot/O94817.html