thioredoxin domain-containing protein 5; endoplasmic reticulum resident protein 46; ER protein 46; ERp46; thioredoxin-like protein p46 (TXNDC5 TLP46 UNQ364/PRO700)

Function

• possesses thioredoxin activity
• able to reduce insulin disulfide bonds

Structure

• belongs to the protein disulfide isomerase family
• contains 3 thioredoxin domains

Compartment

endoplasmic reticulum lumen (putative)

Comparative biology

• complements protein disulfide-isomerase deficiency in yeast (putative)

More general terms

• thioredoxin domain-containing protein
• thioredoxin-like protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=81567
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:81567
• UniProt: http://www.uniprot.org/uniprot/Q8NBS9.html