neuropeptide B; preproprotein L7; hPPL7; contains:neuropeptide B-23; NPB23; hL7; neuropeptide B-29; NPB29; hL7C (NPB, PPL7, PPNPB)

Function

• 2 neuropeptides, neuropeptide B-23 & neuropeptide B-29 derived from a common precursor
• involved in regulation of feeding, neuroendocrine system, memory, learning & in the afferent pain pathway

Compartment

secreted

Expression

• widely expressed in the CNS
• high levels
  • substantia nigra, hypothalamus, hippocampus, spinal cord, placenta, fetal brain
• lower levels
  • testis, uterus, ovary

Pathology

• high levels in colorectal adenocarcinoma

More general terms

• neuropeptide

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=256933
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:256933
• OMIM: https://mirror.omim.org/entry/607996
• UniProt: http://www.uniprot.org/uniprot/Q8NG41.html