cyclin-dependent kinase-18 (CDK18); serine/threonine protein kinase PCTAIRE-3; PCTAIRE-motif protein kinase 3 (PCTK3)

Function

• may play a role in signal transduction cascades in terminally differentiated cells

Structure

• belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
• contains 1 protein kinase domain

Alternative splicing

named isoforms=3

Expression

• expression of isoform 3 is limited to several subcortical nuclei of the basal gangli & the spinal cord
• isoform 2 is widely expressed

More general terms

• cyclin-dependent kinase (CDK)
• serine/threonine kinase PCTAIRE

Database

• UniProt: http://www.uniprot.org/uniprot/Q07002.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5129
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5129
• OMIM: https://mirror.omim.org/entry/169190