myotubularin-related protein 1 (MTMR1)

Function

• lipid phosphatase
• acts on phosphatidylinositol 3-phosphate & phosphatidylinositol (3,5)-bisphosphate
• interacts with MTMR12

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class myotubularin subfamily
• contains 1 GRAM domain
• contains 1 myotubularin phosphatase domain

Compartment

• cell membrane; peripheral membrane protein; cytoplasmic side

Alternative splicing

named isoforms=2

More general terms

• myotubularin family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8776
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8776
• OMIM: https://mirror.omim.org/entry/300171
• UniProt: http://www.uniprot.org/uniprot/Q13613.html
• UniProt: http://www.uniprot.org/uniprot/Q13613.html