interleukin-9 receptor (IL9 receptor, CD129)

Function

receptor for interleukin-9

Structure

• the WSXWS motif appears to be necessary for proper protein folding, efficient intracellular transport & cell-surface receptor binding
• the box 1 motif is required for JAK interaction &/or activation
• belongs to the type I cytokine receptor family, type 4 subfamily
• contains 1 fibronectin F3 module

Compartment

• cell membrane
• secreted

Notes

• the gene encoding for this protein is located in the pseudoautosomal region 2 (PAR2) of X & Y chromosomes

More general terms

• hematopoietin receptor superfamily
• interleukin receptor
• glycoprotein
• CD antigen

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3581
• OMIM: https://mirror.omim.org/entry/300007
• UniProt: http://www.uniprot.org/uniprot/Q01113.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3581