adenyl cyclase-8 (ADCY8, Ca+2/calmodulin-activated adenyl cyclase, ATP pyrophosphate-lyase 8)

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Function

ATP <--> 3',5'-cyclic AMP + diphosphate

Cofactor: binds 2 Mg+2 per subunit (putative)

Structure

Compartment

membrane

Expression

richest source is the hippocampus

More general terms

References

  1. Cooper et al Adenylyl cyclases and the interaction between calcium and cAMP signalling. Nature 374:421 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7700350
  2. UniProt http://www.uniprot.org/uniprot/P40145.html

Database