adenyl cyclase-7 (ATP pyrophosphate-lyase 7, ADCY7, KIAA0037)

Function

• membrane-bound, Ca+2-inhibitable adenylyl cyclase
• stimulated by protein kinase C, & Gs-alpha[GTP], but is unaffected by Ca+2/calmodulin

ATP <--> 3',5'-cyclic AMP + diphosphate

Cofactor: binds 2 Mg+2 per subunit (putative)

Structure

• belongs to the adenylyl cyclase class-4/guanylyl cyclase family
• contains 2 guanylate cyclase domains

Compartment

membrane

Expression

richest source is cerebellum

More general terms

• adenyl cyclase, adenylyl cyclase or adenylate cyclase
• transmembrane 12 protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:113
• OMIM: https://mirror.omim.org/entry/600385
• UniProt: http://www.uniprot.org/uniprot/P51828.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=113