TBC1 domain family member 15; GTPase-activating protein RAB7; GAP for RAB7; Rab7-GAP (TBC1D15)

Function

• GTPase activating protein for RAB7A
• no GTPase activating activity for RAB4, RAB5 or RAB6 (putative)

Structure

contains 1 Rab-GAP TBC domain

Compartment

cytoplasm

Alternative splicing

named isoforms=3

Notes

• at least one isoform may contain a phosphoserine at Ser205 &/or Ser213

More general terms

• TBC1 domain family member

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64786
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:64786
• OMIM: https://mirror.omim.org/entry/612662
• UniProt: http://www.uniprot.org/uniprot/Q8TC07.html