TBC1 domain family member 8; vascular Rab-GAP/TBC-containing protein; AD-3 (TBC1D8, VRP)

Function

• GTPase activating protein for Rab family protein (putative)

Structure

• the arginine & glutamine fingers are critical for the GTPase-activating mechanism
• contains 2 GRAM domains
• contains 1 Rab-GAP TBC domain

Alternative splicing

named isoforms=2

More general terms

• TBC1 domain family member

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11138
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11138
• UniProt: http://www.uniprot.org/uniprot/O95759.html