neurogenin-2; NGN-2; class A basic helix-loop-helix protein 8; bHLHa8; protein atonal homolog 4 (NEUROG2 ATOH4 BHLHA8 NGN2)
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Function
- transcriptional regulator
- role in neuronal differentiation
- activates transcription by binding to the E box (5'-CANNTG-3')
- efficient DNA binding requires dimerization with another bHLH protein (putative)
Structure
- contains 1 basic helix-loop-helix (bHLH) domain