homeobox protein DBX1 (developing brain homeobox protein 1, DBX1)
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Function
- role in patterning the central nervous system during embryogenesis (putative)
- role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 & V1 neurons
- regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path & axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (putative)
Structure
- belongs to the H2.0 homeobox family
- contains 1 homeobox DNA-binding domain