homeobox/POU domain protein RDC-1; POU domain class 4 transcription factor 1; brain-specific homeobox/POU domain protein 3A; Brn-3A; Oct-T1 (POU4F1, BRN3A, RDC1)

Function

• probable transcription factor
• may play a role in regulation of specific gene expression within a subset of neuronal lineages
• may play a role in determining or maintaining identities of a small subset of visual system neurons

Structure

• belongs to the POU transcription factor family, class-4 subfamily
• contains 1 homeobox DNA-binding domain
• contains 1 POU-specific domain

Compartment

nucleus

Expression

• brain
• seems to be specific to the retina
• present in the developing brain, spinal cord & eye
• expression peaks early in embryogenesis (day 13.5) & is undetectable 14 days after birth

More general terms

• homeobox protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q01851.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5457
• OMIM: https://mirror.omim.org/entry/601632