homeobox protein EMX1; empty spiracles homolog 1; empty spiracles-like protein 1 (EMX1)

Function

• transcription factor, which in cooperation with EMX2, acts to generate boundary between the roof & archipallium in the developing brain
• may function in combinations with OTX1/2 to specify cell fates in the developing central nervous system

Structure

• belongs to the EMX homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2

Expression

cerebral cortex

More general terms

• homeobox protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q04741.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2016
• OMIM: https://mirror.omim.org/entry/600034
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2016