coagulation factor IXa

Function

• vitamin K-dependent serine protease
• proteolytically activates factor X to form factor Xa
• selective cleavage of Arg-|-Ile bond in factor X to form factor Xa

Pharmacology

• Available under the name BeneFix (Baxter and American home Products)
• Used to treat hemophilia B

More general terms

• coagulation factor
• serine protease trypsin family

Additional terms

• coagulation cascade
• coagulation factor IX; Christmas factor; plasma thromboplastin component; PTC; contains: coagulation factor IXa light chain; coagulation factor IXa heavy chain (F9)