cytochrome P450 3A5 (P450-PCN3, CYP3A5)

Function

• NADPH-dependent electron transport pathway
• oxidizes a variety of structurally unrelated compounds, including
  • steroids, fatty acids, xenobiotics

Structure

belongs to the cytochrome P450 family

Compartment

membrane-bound, endoplasmic reticulum

Expression

expressed in liver

Laboratory

• CYP3A5 gene mutation

More general terms

• cytochrome P450 3A (CYP3A)

Database

• UniProt: http://www.uniprot.org/uniprot/P20815.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1577
• OMIM: https://mirror.omim.org/entry/605325
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1577