sulfotransferase 6B1; ST6B1; thyroxine sulfotransferase (SULT6B1)

Function

• specifically a sulfotransferase activity towards thyroxine
• role in the metabolism of thyroxine

3'-phosphoadenylyl sulfate + thyroxine = adenosine 3',5'-bisphosphate + thyroxine-sulfate

Structure

belongs to the sulfotransferase 1 family

Compartment

cytoplasm (putative)

Alternative splicing

• named isoforms=2
• additional isoforms seem to exist

Expression

• specifically expressed in kidney & testis

More general terms

• sulfotransferase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=391365
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:391365
• UniProt: http://www.uniprot.org/uniprot/Q6IMI4.html