glutathione S-transferase theta-2 (GST class-theta-2, GSTT2)

Function

• conjugation of reduced glutathione to a wide number of exogenous & endogenous hydrophobic electrophiles
• has a sulfatase activity

RX + glutathione = HX + R-S-glutathione

Structure

• homodimer
• belongs to the GST superfamily, Theta family

Compartment

cytoplasm

Expression

• expressed at low levels in liver
• In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages & alveolar type-2 cells

More general terms

• glutathione transferase

Additional terms

• glutathione S-transferase theta-2B (GSTT2B)

Database

• UniProt: http://www.uniprot.org/uniprot/P0CG29.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2953
• OMIM: https://mirror.omim.org/entry/600437