dihydrolipamide succinyltransferase E2 (DLST)

Function

• component of the 2-oxoglutarate dehydrogenase complex
  • the 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA & CO2
  • it contains multiple copies of 3 enzymatic components:
    • 2-oxoglutarate dehydrogenase E1
    • dihydrolipoamide succinyltransferase E2 = this protein
    • lipoamide dehydrogenase E3

More general terms

• acyltransferase

Component of

• alpha-ketoglutarate dehydrogenase

Database

• UniProt: http://www.uniprot.org/uniprot/P36957.html
• OMIM: https://mirror.omim.org/entry/126063