3-oxo-5-alpha-steroid 4 dehydrogenase; steroid 5-alpha reductase; testosterone 5-alpha reductase
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Introduction
Catalyzes reduction of testosterone to form dihydrotestosterone.
Pharmacology
- 5-alpha reductase inhibitors are used for treatment of
More general terms
More specific terms
- 3-oxo-5-alpha-steroid 4 dehydrogenase 1; steroid 5-alpha reductase 1; testosterone 5-alpha reductase 1; SR type 1 (SRD5A1, S5AR)
- 3-oxo-5-alpha-steroid 4 dehydrogenase 2; steroid 5-alpha reductase 2; testosterone 5-alpha reductase 2; 5 alpha-SR2; type II 5-alpha reductase; SR type 2 (SRD5A2)
- 3-oxo-5-alpha-steroid 4-dehydrogenase 3; steroid 5-alpha reductase 3; testosterone 5-alpha reductase 3; SR type 3; steroid 5-alpha-reductase 2-like (SRD5A3, SRD5A2L)
Additional terms
References
- ↑ Melcangi RC, Celotti F, Ballabio M, Poletti A, Martini L. Testosterone metabolism in peripheral nerves: presence of the 5 alpha-reductase-3 alpha-hydroxysteroid-dehydrogenase enzymatic system in the sciatic nerve of adult and aged rats. J Steroid Biochem. 1990 Jan;35(1):145-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2308325