AP-1 complex subunit mu-2; adaptor-related protein complex 1 mu-2 subunit; adaptor protein complex AP-1 mu-2 subunit; Golgi adaptor HA1/AP1 adaptin mu-2 subunit; Mu-adaptin 2; AP-mu chain family member mu1B; mu1B-adaptin; clathrin assembly protein complex 1 medium chain 2 (AP1M2)

Function

• subunit of clathrin-associated adaptor protein complex 1 (AP-1)
• phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals (putative)

Structure

• belongs to the adaptor complexes medium subunit family
• contains 1 MHD (mu homology) domain

Compartment

• Golgi, cytoplasmic vesicle
• clathrin-coated vesicle membrane
• peripheral membrane, cytoplasmic side
• component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex

Alternative splicing

named isoforms=2

More general terms

• mu adaptin (adaptor-related protein complex, mu subunit)
• phosphoprotein

Additional terms

• clathrin (triskelion)

Component of

• HA1/AP1 adaptor complex (clathrin assembly protein [AP]-1)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1005
• OMIM: https://mirror.omim.org/entry/607309
• UniProt: http://www.uniprot.org/uniprot/Q9Y6Q5.html