solute carrier family 45 member 3 (SLC45A3, prostate cancer-associated protein 6, prostein, PCANAP6, PRST)

Structure

• belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family

Compartment

membrane (putative)

Expression

• prostate-specific, marker for prostate cells
• expressed in all prostatic glandular cells
• expressed both in normal prostate & in prostate cancer
• up-regulated by androgens

Pharmacology

• in case of prostate cancers, may be useful as target antigen for prostate carcinoma-directed cytotoxic T-cell lymphocytes

More general terms

• solute carrier family 45 (SLC45, SLC45A)
• transmembrane 11 protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8541
• OMIM: https://mirror.omim.org/entry/608319
• UniProt: http://www.uniprot.org/uniprot/Q96JT2.html