glucose-6-phosphatase 3 (G6Pase 3, G-6-Pase 3, ubiquitous glucose-6-phosphatase catalytic subunit-related protein, glucose-6-phosphatase beta, G6Pase-beta, G6PC3, UGRP)

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Function

D-glucose 6-phosphate + H2O <--> D-glucose + phosphate

Kinetic parameters:

  • KM=1.0 mM for glucose-6-phosphate (at pH 5.5.)
  • KM=2.0 mM for glucose-6-phosphate (at pH 6.5.)

Structure

belongs to the glucose-6-phosphatase family

Compartment

Expression

Pathology

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/Q9BUM1.html
  2. 2.0 2.1 Martin CC Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein. J Mol Endocrinol 2002, 29:205 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12370122
  3. Boztug K et al. A syndrome with congenital neutropenia and mutations in G6PC3. N Engl J Med 2009 Jan 1; 360:32. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19118303
    Dale DC and Link DC. The many causes of severe congenital neutropenia. N Engl J Med 2009 Jan 1; 360:3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19118300

Database