solute carrier family 27 member 6 (SLC27A6, long-chain fatty acid transport protein 6, fatty acid transport protein 6, FATP-6, very long-chain acyl-CoA synthetase homolog 1, VLCSH1, hVLCS-H1, very long-chain fatty-acid-coenzyme A ligase 2, ACSVL2, FACVL2, FATP1)

Function

• role in translocation of long-chain fatty acids across the plasma membrane
• predominant fatty acid protein transporter in heart

Structure

• belongs to the ATP-dependent AMP-binding enzyme family

Compartment

• membrane (putative)
• cell membrane, sarcolemma (putative)
• in heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36

Expression

• strongly expressed in heart & localizes to cardiac myocytes
• expressed at moderate levels in placenta, testis, & adrenal glands
• expressed at very low levels in kidney, bladder & uterus

More general terms

• transmembrane 2 protein
• solute carrier family 27 (SLC27, SLC27A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2896
• OMIM: https://mirror.omim.org/entry/604196
• UniProt: http://www.uniprot.org/uniprot/Q9Y2P4.html