zinc finger protein basonuclin-2 (BNC2)

Function

• transcription factor specific for skin keratinocytes.
• differentiation of spermatozoa & oocytes (putative)

Structure

• belongs to the krueppel C2H2-type zinc-finger protein family
• contains 4 C2H2-type zinc fingers

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• expressed in testis, uterus, small intestine > colon, prostate, skin, primary keratinocytes, immortalized keratinocytes, HeLa cells Not detected in blood,thymus, spleen, HepG2 cells

More general terms

• C2H2 type zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/608669
• UniProt: http://www.uniprot.org/uniprot/Q6ZN30.html