zinc finger protein 37 homolog; Zfp-37 (ZFP37)

Function

• may be involved in transcriptional regulation

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 12 C2H2-type Zn+2 fingers
• contains 1 KRAB domain

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2

Expression

• expressed at low level in several tissues, including fetal cartilage

Notes

• uncertain whether Met-1 or Met-34 is the initiator
• orthologous sequences start at a downstream Met

More general terms

• C2H2 type zinc finger protein
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7539
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7539
• OMIM: https://mirror.omim.org/entry/602951
• UniProt: http://www.uniprot.org/uniprot/Q9Y6Q3.html