zinc finger protein PLAGL1; lost on transformation 1; LOT-1; pleiomorphic adenoma-like protein 1; tumor supressor ZAC (PLAGL1, LOT1, ZAC)

Function

• weak transcriptional activator
• transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide
• interacts with THRSP

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 7 C2H2-type Zn+2 fingers

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• C2H2 type zinc finger protein
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5325
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5325
• OMIM: https://mirror.omim.org/entry/603044
• UniProt: http://www.uniprot.org/uniprot/Q9UM63.html