zinc finger protein ZIC4; zinc finger protein of the cerebellum 4 (ZIC4)

Function

• binds to DNA (putative)

Structure

• belongs to the GLI C2H2-type Zn+2-finger protein family
• contains 5 C2H2-type Zn+2 fingers

Compartment

nucleus (putative)

Alternative splicing

• named isoforms=2
• may be due to an intron retention

Laboratory

• ZIC4 Ab in serum

Notes

• uncertain whether Met-1 is the initiator

More general terms

• zinc finger protein of the cerebellum (ZIC)
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84107
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:84107
• OMIM: https://mirror.omim.org/entry/608948
• UniProt: http://www.uniprot.org/uniprot/Q8N9L1.html