zinc finger protein 518 (ZNF518, ZNF518A)

From Aaushi
Jump to navigation Jump to search

Function

* protein-truncating variants in ZNF518A are associated with earlier age at menopause (by 5.61 years) & later age at menarche (by 0.56 years)[2]

Structure

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/Q6AHZ1.html
  2. 2.0 2.1 Ledford H Why some women enter menopause early - and how that could affect their cancer risk. Nature. 11 September 2024 PMID: https://www.ncbi.nlm.nih.gov/pubmed/39261698 https://www.nature.com/articles/d41586-024-02905-5
    Stankovic S, Shekari S, Huang QQ et al Genetic links between ovarian ageing, cancer risk and de novo mutation rates. Nature. 2024 Sep 11. PMID: https://www.ncbi.nlm.nih.gov/pubmed/39261734 https://www.nature.com/articles/s41586-024-07931-x

Database