ADP-ribosylation factor-like protein 3 (ARL3, ARFL3)

Function

• required for normal cytokinesis
• interacts with RP2, SYS1 & SCOC

Structure

belongs to the small GTPase superfamily, Arf family

Compartment

• Golgi membrane
• peripheral membrane protein, cytoplasmic side
• spindle. nucleus
• present on the mitotic spindle

Pathology

• does not act as an allosteric activator of the cholera toxin catalytic subunit

More general terms

• ADP-ribosylation factor-like protein (ARL)

Database

• UniProt: http://www.uniprot.org/uniprot/P36405.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=403
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:403
• OMIM: https://mirror.omim.org/entry/604695