GTP-binding regulatory protein Gt alpha-1 (guanine nucleotide binding protein Gt alpha-1, heterotrimeric G-protein Gt alpha-1, transducin alpha-1, rod transducin alpha, GNAT1)
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Function
- Gt-alpha subunit of Gt protein (transducin) that couples rhodopsin with cGMP phosphodiesterase
- target of Gt1-alpha-GTP is cGMP phosphodiesterase
Structure
belongs to the Gt-alpha family
Expression
Pathology
- defects in GNAT1 are the cause of autosomal dominant congenital stationary night blindness 3
More general terms
Additional terms
References
- ↑ Bourne HR et al, The GTPase superfamily: a conserved switch for diverse cell functions Nature 348:125 1990 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2122258
- ↑ Mutations of the GNAT1 gene, Retina International's Scientific Newsletter http://www.retina-international.com/sci-news/gntmut.htm
- ↑ UniProt http://www.uniprot.org/uniprot/P11488.html