sry-box-17 protein (sox17)

Function

• probable transcriptional activator in premeiotic germ cells
• binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3' (putative)

Structure

contains 1 HMG box DNA-binding domain

Compartment

nucleus (putative)

Expression

• expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, & kidney
• in normal gastrointestinal tract, expressed in esophagus, stomach & small intestine > colon & rectum

More general terms

• sox protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6432
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64321
• UniProt: http://www.uniprot.org/uniprot/Q9H6I2.html