superkiller viralicidic activity 2-like 2; ATP-dependent helicase SKIV2L2 (SKIV2L2, KIAA0052, Mtr4)

Function

• may be involved in pre-mRNA splicing
• associated with the RNA exosome complex & involved in 3'processing of the 7S pre-RNA to the mature 5.8S rRNA
• associated with the RNA exosome complex
• identified in the spliceosome C complex

Structure

• belongs to the helicase family, SKI2 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus, nucleolus

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)

Component of

• exosome multienzyme ribonuclease complex
• spliceosome C complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23517
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23517
• UniProt: http://www.uniprot.org/uniprot/P42285.html