keratin-associated protein 5-8 (keratin-associated protein 5.8, ultrahigh sulfur keratin-associated protein 5.8, keratin ultra high-sulfur matrix protein B, UHS keratin B, UHS KerB, KRTAP5-8, KAP58, KRTAP58, UHSKB)

Function

• hair keratin-associated protein (KRTAP)
• essential for formation of a rigid & resistant hair shaft via extensive disulfide bond cross-linking with abundant Cys of hair keratins
• high-sulfur keratin matrix protein

Structure

belongs to the KRTAP type 5 family

Expression

• restricted to hair root
• not detected in any other tissues
• expressed in cuticle layers of differentiating hair follicles

More general terms

• ketatin-associated protein (KRTAP)

Additional terms

• hair

Database

• UniProt: http://www.uniprot.org/uniprot/O75690.html