general transcription factor IIH subunit 4; basic transcription factor 2 52 kD subunit; BTF2 p52; general transcription factor IIH polypeptide 4; TFIIH basal transcription factor complex p52 subunit; p52TFIIH (GTF2H4)

Function

• component of the core-TFIIH basal transcription factor
• role in nucleotide excision repair of DNA
• when complexed to CAK, role in RNA transcription by RNA polymerase 2

Structure

belongs to the TFB2 family

Compartment

nucleus

More general terms

• transcription factor IIH subunit

Component of

• transcription factor IIH (TFIIH) or BTF2

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2968
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2968
• OMIM: https://mirror.omim.org/entry/601760
• OMIM: https://mirror.omim.org/entry/601760
• UniProt: http://www.uniprot.org/uniprot/Q92759.html