P2Y9 purinoceptor; lysophosphatidic acid receptor 4; LPA receptor 4; LPA-4; P2Y purinoceptor 9; P2Y9; purinergic receptor 9; G-protein coupled receptor 23; P2Y5-like receptor (LPAR4, GPR23, LPA4, P2RY9)

Function

• receptor for lysophosphatidic acid (LPA)
• transduces a signal by increasing intracellular Ca+2 & by stimulating adenylyl cyclase activity
• potency for agonists is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• high expression in ovary
• not detected in brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus or hippocampus

More general terms

• P2Y purinoceptor or P2Y purinergic receptor
• lysophosphatidic acid receptor (LPA-R)
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2846
• OMIM: https://mirror.omim.org/entry/300086
• UniProt: http://www.uniprot.org/uniprot/Q99677.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2846