orexin receptor type 1; Ox1r; hypocretin receptor type 1 (HCRTR1)

Function

• moderately selective excitatory receptor for orexin-A &, with a lower affinity, for orexin-B neuropeptide
• seems to be exclusively coupled to the Gq proteins that activate phospholipase C mediated signaling

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

More general terms

• hypocretin receptor; orexin receptor (Hcrtr)
• glycoprotein
• phosphoprotein

Additional terms

• hypocretin; orexin (HCRT, OX, PPORX, PPOX)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3061
• OMIM: https://mirror.omim.org/entry/602392
• UniProt: http://www.uniprot.org/uniprot/O43613.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3061