Metabotropic glutamate receptor 7; mGluR7 (GRM7, GPRC1G, MGLUR7)

Function

• receptor for glutamate
• activity is mediated by a Gi-protein
• interacts with PICK1 (putative)

Structure

belongs to the G-protein coupled receptor 3 family

Compartment

cell membrane

Alternative splicing

named isoforms=5

Expression

• expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, & cerebellum
• expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 & isoform 4

More general terms

• metabotropic glutamate receptor
• phosphoprotein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2917
• OMIM: https://mirror.omim.org/entry/604101
• UniProt: http://www.uniprot.org/uniprot/Q14831.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2917