Metabotropic glutamate receptor 2; mGluR2 (GRM2, GPRC1B, MGLUR2)

Function

• receptor for glutamate
• activity is mediated by a Gi-protein
• may mediate suppression of neurotransmission or may play role in synaptogenesis or synaptic stabilization
• interacts with GRASP (putative)

Structure

belongs to the G-protein coupled receptor 3 family

Compartment

cell membrane

Expression

• widely expressed in different regions of the adult & fetal brain

More general terms

• metabotropic glutamate receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2912
• OMIM: https://mirror.omim.org/entry/604099
• UniProt: http://www.uniprot.org/uniprot/Q14416.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2912