serotonin [5HT]-2B receptor; 5-hydroxytryptamine receptor 2B; 5-HT-2B; serotonin receptor 2B (HTR2B)

Function

• one of several receptors for 5-hydroxytryptamine (serotonin)
• mediates its action by association with G proteins that activate a phosphatidylinositol-Ca+2 second messenger system
• interacts with MPDZ

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane; multi-pass membrane protein

Expression

• detected in most peripheral organs
• only low expression levels were found in the brain

More general terms

• serotonin [5HT]-2 receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3357
• OMIM: https://mirror.omim.org/entry/601122
• UniProt: http://www.uniprot.org/uniprot/P41595.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3357