5-hydroxytryptamine receptor 1D; 5-HT-1D; 5-HT-1D-alpha; serotonin receptor 1D (HTR1D HTR1DA HTRL)

Function

• one of the several receptors for 5-hydroxytryptamine (serotonin)
• activity is mediated by G proteins that inhibit adenylate cyclase (Gi proteins)
• presynaptic autoreceptor on presynaptic axon terminal
• interaction with serotonin turns off further release of serotonin

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

• cell membrane
• presynaptic axon terminal

More general terms

• serotonin [5HT]-1 receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3352
• OMIM: https://mirror.omim.org/entry/182133
• UniProt: http://www.uniprot.org/uniprot/P28221.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3352